Ofie was born Ofuakuor Ofuatey-Kodjoe, in New York City to Dr. W.B. Ofuatey-Kodjoe, a political science professor, and Virginie Ofuatey-Kodjoe (Nee Coussey), a nurse/medical administrator. She is the three, between sister Ayeki and Brother Nene (deceased). 

She grew up in Queens, NY before returning to Ghana, where she attended high school at Aburi Girls Secondary School. She then moved back to the U.S. to pursue her tertiary education in New York.